Table 2 Association of HERC4 expression with patient’s clinicopathological features in 120 invasive ductal carcinoma
From: The expression and clinical significance of HERC4 in breast cancer
Variables | HERC4 staining | |||
|---|---|---|---|---|
Negative(%) | Positive(%) | Total | P valueb | |
Age(years) | ||||
≤50a | 25(45.5) | 30(54.5) | 55 | 0.927 |
>50 | 29(44.6) | 36(55.4) | 65 | |
pT status | ||||
T1 | 15(88.2) | 2(11.8) | 17 | 0.000 |
T2 | 36(42.9) | 48(57.1) | 84 | |
T3 | 3(18.8) | 16(81.2) | 19 | |
Lymph node metastasis | ||||
Negative | 32(80) | 8(20) | 40 | 0.000 |
Positive | 22(27.5) | 58(72.5) | 80 | |
Histology grade | ||||
I | 41(95.3) | 2(4.7) | 43 | 0.000 |
II | 13(24.5) | 40(75.5) | 53 | |
III | 0(0) | 24(100) | 24 | |
Stage | ||||
I-II | 43(76.8) | 13(23.2) | 56 | 0.000 |
III-IV | 11(17.2) | 53(82.8) | 64 | |
ER status | ||||
Negative | 25(43.1) | 33(56.9) | 58 | 0.686 |
Positive | 29(46.8) | 33(53.2) | 62 | |
PR status | ||||
Negative | 31(50) | 31(50) | 62 | 0.255 |
Positive | 23(39.7) | 35(60.3) | 58 | |
HER2 status | ||||
Negative | 15(42.9) | 20(57.1) | 35 | 0.762 |
Positive | 39(45.9) | 46(54.1) | 85 | |
P53 status | ||||
Negative | 23(41.8) | 32(58.2) | 55 | 0.519 |
Positive | 31(47.7) | 34(52.3) | 65 | |
Ki67 status | ||||
Negative | 15(38.5) | 24(61.5) | 39 | 0.318 |
Positive | 39(48.1) | 42(51.9) | 81 | |