Figure 5From: Establishment of a bortezomib-resistant Chinese human multiple myeloma cell line: MMLALInterphase fluorescence in situ hybridization (FISH) analysis of the MMLAL cells. FISH with TP53 locus-specific (red) and chromosome 17 centromeric (green) probes indicates loss of TP53 due to monosomy 17 (arrow) and deletion 17p (arrowhead) in different nucleated cells.Back to article page