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Figure 10 | Cancer Cell International

Figure 10

From: 3,4-dihydroxyphenyl acetic acid and (+)-epoxydon isolated from marine algae-derived microorganisms induce down regulation of epidermal growth factor activated mitogenic signaling cascade in Hela cells

Figure 10

Proposed signaling cascades of the compounds on EGF-induced p44/42 MAPK (Erk1/2) pathways. The compounds inhibited the activities of signal molecules in MAPK pathways and increased release of cytochrome c from mitochondria. It may results in inhibition of cell proliferation and apoptosis in HeLa cells.

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