Figure 7From: 3,4-dihydroxyphenyl acetic acid and (+)-epoxydon isolated from marine algae-derived microorganisms induce down regulation of epidermal growth factor activated mitogenic signaling cascade in Hela cellsImmunofluorescence of the expressions of phosphorylated EGFR. Immunofluorescence was performed as follows by Materials and Methods and the images were captured at 488 nm. In control cells (panels A and D) and cells treated with EGF (10 ng/mL for 10 min, panels B and E), EGF induced the expression of active EGFR (white arrows, brightened) but the increased expression levels were not decreased in the cells treated with both EGF and each compound (panels C and F).Back to article page