Single nucleotide polymorphisms of CD20 gene and their relationship with clinical efficacy of R-CHOP in patients with diffuse large B cell lymphoma

Table 1 Patient’s characteristics and their correlations with CD20 Exon2 _[216] genotype

Clinical parameters	No.	Genotype		P*	Clinical parameters	No.	Genotype		P*
Clinical parameters	No.	CC	CTplusTT	P*	Clinical parameters	No.	CC	CTplusTT	P*
Gender					Bulky mass
Male	83	63	20	0.787	≥10cm	18	11	7	0.249
Female	81	60	21		<10cm	146	112	34
Age					Localized
≤60	102	76	26	0.852	Yes	25	19	6	0.900
>60	62	47	15		No	139	104	35
B symptoms					No Extra Nodal
Positive	62	46	16	0.852	≤1	122	90	32	0.535
Negative	102	77	25		>1	42	33	9
LDH					Incidence site
Positive	77	55	22	0.320	Lymph node	93	68	25	0.524
Negative	87	68	19		Extralymph	71	55	16
β₂-MG					IPI
Positive	49	35	14	0.684	0-2	114	84	30	0.557
Negative	106	79	27		3-5	50	39	11
Stage					Molecular subtypes
I-II	75	55	20	0.651	GCB	28	21	7	0.868
III-IV	89	68	21		Non-GCB	113	83	30

Abbreviations: LDH lactate dehydrogenase level, MG macroglobulin, IPI international prognostic index, GCB germinal centre B cell, *χ² test.

ISSN: 1475-2867