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Table 1 Patient’s characteristics and their correlations with CD20 Exon2 [216] genotype

From: Single nucleotide polymorphisms of CD20 gene and their relationship with clinical efficacy of R-CHOP in patients with diffuse large B cell lymphoma

Clinical parameters No. Genotype P* Clinical parameters No. Genotype P*
CC CTplusTT CC CTplusTT
Gender      Bulky mass     
 Male 83 63 20 0.787  ≥10cm 18 11 7 0.249
 Female 81 60 21    <10cm 146 112 34  
Age      Localized     
 ≤60 102 76 26 0.852  Yes 25 19 6 0.900
 >60 62 47 15    No 139 104 35  
B symptoms      No Extra Nodal     
 Positive 62 46 16 0.852  ≤1 122 90 32 0.535
 Negative 102 77 25    >1 42 33 9  
LDH      Incidence site     
 Positive 77 55 22 0.320  Lymph node 93 68 25 0.524
 Negative 87 68 19    Extralymph 71 55 16  
β2-MG      IPI     
 Positive 49 35 14 0.684  0-2 114 84 30 0.557
 Negative 106 79 27    3-5 50 39 11  
Stage      Molecular subtypes     
 I-II 75 55 20 0.651  GCB 28 21 7 0.868
 III-IV 89 68 21    Non-GCB 113 83 30  
  1. Abbreviations: LDH lactate dehydrogenase level, MG macroglobulin, IPI international prognostic index, GCB germinal centre B cell, *χ2 test.