Skip to main content

Table 3 Detection (n d ) and quantification (n q ) incidences, concentration ranges and medians in the headspace of medium and cell cultures

From: Release and uptake of volatile organic compounds by human hepatocellular carcinoma cells (HepG2) in vitro

  

Experiment No

Incidence nd(nq)

Range (median)

Experiment No

Incidence nd(nq)

Range (median)

1

2

3

4

5

6

1

2

3

4

5

6

Uptake

Isoprene

2.1

2.6

0.9

8.5

2.2

1.6

6(6)

0.9-8.5(2.2)

7.6

11.9

1.7

18

9.3

13.5

6(6)

1.7-18(10.5)

2-Propenal, 2-methyl-

0.26

0.21

0.28

0.30

0.43

0.41

6(6)

0.21-0.43(0.29)

1.0

0.62

0.85

2.07

0.71

0.68

6(6)

0.58-2.07 (0.73)

Propanal, 2-methyl-

0.87

0.92

0.9

0.96

1.18

1.10

6(4)

0.9-1.18(0.94)

42.5

50.9

32.5

160

47.4

54.4

6(6)

32.5-160(49)

2-Ethylacrolein

1900

2900

2930

1940

1570

1580

6

1574-2923(1937)

16000

19500

4760

10900

4880

5100

6

4758-19500 (8020)

Butanal, 3-methyl-

0.8

1.07

n.d.

1.48

n.d.

n.d.

3(3)

0.8-1.48(1.07)

70.5

79.8

51

399

122

126

6(6)

51-399(100)

n-Hexanal

1.3

0.9

1.0

0.56

0.50

0.51

6(6)

0.5-1.3(0.74)

11

12.8

6.0

11

2.7

3.0

6(6)

2.7-13(8.5)

n-Propyl propionate

0.15

1.46

1.38

n.q.

n.d.

n.d.

4(3)

0.15-1.46(1.0)

5.37

5.2

3

3.84

4.17

3.68

6(6)

3.7-5.4(4.1)

n-Butyl acetate

0.3

0.52

0.28

2.9

0.17

0.2

6(6)

0.17-2.9(0.3)

6.5

9.8

2.3

4.8

1.47

2.12

6(6)

1.5-9.8(3.4)

 

Benzaldehyde

0.31

0.27

0.6

0.29

0.31

0.3

6(6)

0.27-0.6(0.3)

1.5

1.63

1.57

13.8

3.14

2.96

6(6)

1.5-14(2.4)

Release

Dimethyl sulfide

12.8

12.4

7.5

80

69

77

6(6)

7.5-80.3(43)

9

8.2

4

8

9.5

10.9

6(6)

4-11(8.6)

Sulfide, ethyl methyl

0.11

0.12

n.q.

0.29

0.26

0.23

6(5)

0.11-0.29(0.23)

n.d.

n.d.

n.d.

n.d.

n.d.

n.d.

0(0)

n.d.

2-Pentanone

3.3

4

1.8

3.6

4.0

4.0

6(6)

1.8-4.0(3.8)

0.18

0.2

0.15

0.7

0.65

0.7

6(5)

0.15-0.7(0.45)

n-Propyl acetate

0.59

0.62

0.22

0.27

0.32

0.22

6(6)

0.22-0.62(0.33)

n.d.

n.d.

n.q.

n.q.

n.q.

n.q.

4(0)

n.q.

Thiophene, 3-methyl-

0.07

0.09

0.03

0.12

0.16

0.12

6(6)

0.03-0.16(0.11)

n.q.

n.q.

n.q.

0.03

0.05

0.04

6(3)

0.03-0.05(0.04)

2-Heptene

2500

4200

3700

2700

2600

1500

6

1512-4170(2680)

680

710

950

500

600

480

6

500-950(600)

Propane, 2-methyl-1-(methylthio)-

650

580

350

6400

5900

5800

6

346-6400(3200)

-

-

-

-

-

-

0

-

3-Heptanone

0.23

0.89

0.36

0.2

0.2

0.14

6(6)

0.13-0.9(0.22)

0.14

0.17

0.12

0.09

0.09

0.08

6(6)

0.09-0.17(0.1)

2-Heptanone

0.36

0.44

0.19

0.76

0.66

0.67

6(6)

0.19-0.76(0.55)

n.q.

n.q.

n.q.

0.4

0.09

0.23

6(3)

0.09-0.4(0.25)

Furan, 2-methyl-5-(methylthio)-

6.4

6.9

2

2.4

2.1

2.0

6(6)

2.0-6.9(2.3)

n.d.

n.d.

n.d.

n.d.

n.d.

n.d.

0(0)

n.d.

3-Octanone

0.82

0.92

1.03

0.37

0.36

0.39

6(6)

0.36-1.03(0.6)

n.d.

n.d.

n.d.

n.d.

n.d.

n.d.

0(0)

n.d.

 

2-Nonanone

3.2

3.6

1.8

1.8

1.7

1.8

6(6)

1.73-3.56(1.8)

n.q.

n.q.

n.q.

n.q.

n.q.

n.q.

6(0)

n.q.

  1. Compounds in italics were not quantified for reasons mentioned in the text, n.d. – not detected (<LOD), n.q. - not quantified (<LOQ).