Figure 2
From: Tumor cell response to bevacizumab single agent therapy in vitro
Gene expression analysis in bevacizumab treated tumor cells. Change in relative expression of (A) VEGFA isoforms, (B) VEGFR1, (C) NRP1 and (D) VEGFR2 in bevacizumab treated cells after 24 hours of hypoxia versus untreated hypoxic cells. Only cell lines with detectable expression are included. * indicates HUVECs were in addition stimulated with rhVEGF in the absence of bevacizumab and normalized against untreated controls.