Tumor cell response to bevacizumab single agent therapy in vitro

Table 1 Protein and cell surface expression of VEGFR1, VEGFR2 and NRP1

		NSCLC		CRC			RCC	BC
		H522	HOP62	HCT-116	HT-29	KM12	A498	HS-578 T	MDA-MB-231	HUVEC
Protein expression	VEGFR1	-	+	-	+	-	+	+	+	+
	VEGFR2	+	-	+	n.d.	-	-	-	+	+
	NRP1	+	+	+	+	+	+	+	+	-
Cell surface expression	VEGFR1	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.	n.d.
	VEGFR2	-	-	-	-	-	-	-	+	+
	NRP1	-	+	-	-	-	+	+	+	-

ISSN: 1475-2867