Skip to main content

Advertisement

Table 2 Gene frequency of rs1229984 (ADH1B) between esophageal cancer and control group

From: Single nucleotide polymorphism at alcohol dehydrogenase-1B is associated with risk of esophageal squamous cell carcinoma

Genotype ESGG OR* (95% CI) P
Patients (n = 1001) No. (%) Controls (n = 1391) No. (%)
AA 377 (37.66) 663 (47.66) 1.00 (reference)  
AG 400 (39.96) 578 (41.55) 1.20 (1.00–1.44) 0.06
GG 224 (22.38) 150 (10.79) 2.81 (2.18–3.62) 1.05 × 10-15
AG + GG 624 (62.34) 728 (52.34) 1.51 (1.28–1.80) 1.95 × 10-6
G allele frequency 42.36% 31.56%   
P trend    <0.01  
  1. *Data were calculated by logistic regression, adjusted for age, sex, smoking.
  2. †Tests for trend of odds within genotypes of AA, AG, GG were two sided and based on likelihood ratio tests assuming a multiplicative model.