Table 1 The mechanical properties of tumor-retrieved cells and in vitro cultured LLC cells under no treatment, TGF-β1 treatment and SB-505124 + TGF-β1 co-treatment
Tumor-retrieval | In vitro | ||
|---|---|---|---|
Non-Rec | Control | ||
CS (Pa) | 428.7 ± 22.9 (N = 118) | CS (Pa) | 384.9 ± 15.4 (N = 12) |
TS (Pa) | 601.8 ± 34.6 (N = 92) | TS (Pa) | 530.5 ± 9.9 (N = 14) |
AF (nN) | 32.58 ± 1.7 (N = 88) | AF (nN) | 27.45 ± 3.2 (N = 9) |
AFM (Pa) | 758.1 ± 134.8 (N = 54) | ||
Rec | TGF-β1 | ||
CS (Pa) | 539.1 ± 32.7 (N = 98)** | CS (Pa) | 465.5 ± 29.2 (N = 13)** |
TS (Pa) | 693.4 ± 44.9 (N = 108)** | TS (Pa) | 593.7 ± 42.6 (N = 14)** |
AF (nN) | 38.56 ± 2.3 (N = 110)* | AF (nN) | 54.04 ± 9.1 (N = 15)*** |
AFM (Pa) | 1095.0 ± 176.6 (N = 50)** | ||
SB-505124 + TGF-β1 | |||
CS (Pa) | 404.9 ± 15.4 (N = 18) | ||
TS (Pa) | 560.5 ± 9.9 (N = 18) | ||
AF (nN) | 33.5 ± 3.2 (N = 12) | ||