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Figure 8 | Cancer Cell International

Figure 8

From: Epigenetic alteration by DNA-demethylating treatment restores apoptotic response to glucocorticoids in dexamethasone-resistant human malignant lymphoid cells

Figure 8

Expression and regulation of three modulators of GR actions in IIE6, a Dex-sensitive revertant clone from RPMI 8226 cells. RNA was quantified using real-time PCR as described in d Methods. Shown are the RNA expression levels, before and after Dex treatment, for GR CoActivators PGC-1a and c-Myb, and the GR CoRepressor PU.1. The inset shows the c-Myb data on an expanded ordinate.

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