The association between hypoxia-inducible factor-1 α gene G1790A polymorphism and cancer risk: a meta-analysis of 28 case–control studies

Zhou, Yuqiao; Lin, Lin; Wang, Yun; Jin, Xin; Zhao, Xin; Liu, Dongjuan; Hu, Ting; Jiang, Lu; Dan, Hongxia; Zeng, Xin; Li, Jing; Wang, Jiayi; Chen, Qianming

doi:10.1186/1475-2867-14-37

Table 1 Characteristics of populations and cancer types of the studies included in the meta-analysis

From: The association between hypoxia-inducible factor-1 α gene G1790A polymorphism and cancer risk: a meta-analysis of 28 case–control studies

Author	Year	Country	Ethnicity	Cancer site	Case–control	Gender^a	Soure of control	Genotyping method	HWE
Ribeiro AL	2013	Portugal	Caucasian	Breast cancer	96/74	Female	HB	PCR-RFLP	0.00
Alves LR	2012	Brazil	Brazilian	Head and neck cancer	88/40	Mixed	PB	PCR-RFLP	0.69
Li P	2012	China	Asian	Prostate cancer	662/716	Male	PB	TaqMan	0.55
Mera-Menendez F	2012	Spain	Caucasian	Head and neck cancer	121/154	Mixed	PB	PCR–RFLP	0.69
Ruiz-Tovar J	2012	Spain	Caucasian	Pancreatic cancer	59/159	Mixed	PB	PCR-RFLP	0.68
Kuo WH	2012	China	Asian	Lung cancer	285/300	Mixed	PB	PCR–RFLP	0.15
Qin C	2012	China	Asian	Renal cell carcinoma	620/623	Mixed	PB	PCR-RFLP	0.42
Wang X	2011	China	Asian	Pancreatic cancer	263/271	Mixed	PB	PCR-RFLP	0.49
Putra AC	2011	Japan	Asian	Lung cancer	83/110	Mixed	PB	PCR	0.65
Kim YH	2011	Korea	Asian	Other cancer	199/215	Female	PB	PCR-RFLP	0.14
Shieh TM	2010	China	Asian	Head and neck cancer	305/96	Mixed	PB	PCR-RFLP	0.71
Hsiao PC	2010	China	Asian	Other cancer	102/347	Mixed	HB	PCR-RFLP	0.70
Chen MK	2009	China	Asian	Head and neck cancer	174/347	Mixed	PB	PCR-RFLP	0.70
Naidu R	2009	Malaysia	Asian	Breast cancer	410/275	Female	PB	PCR-RFLP	0.90
Konac E	2009	Turkey	Caucasian	Lung cancer	141/156	Mixed	HB	PCR-RFLP	0.94
Li K	2009	China	Asian	Other cancer	87/106	Mixed	PB	PCR	0.76
Munoz-Guerra MF	2009	Spain	Caucasian	Head and neck cancer	74/139	Mixed	PB	PCR-RFLP	0.69
Kim HO	2008	Korea	Asian	Breast cancer	90/102	Female	PB	PCR	0.06
Apaydin I	2008	Turkey	Caucasian	Breast cancer	102/102	Female	PB	PCR-RFLP	0.84
Li H	2007	USA	Mixed	Prostate cancer	1072/1271	Male	PB	PCR-RFLP	0.81
Orr-Urtreger A	2007	Israel	Caucasian	Prostate cancer	402/300	Male	PB	PCR-RFLP	0.95
Fransen K	2006	Sweden	Caucasian	Other cancer	198/258	Mixed	PB	PCR-RFLP	0.77
Konac E-O ^b	2007	Turkey	Caucasian	Other cancer	49/107	Female	PB	PCR-RFLP	0.00
Konac E-C ^c	2007	Turkey	Caucasian	Other cancer	32/107	Female	PB	PCR-RFLP	0.00
Konac E-E ^d	2007	Turkey	Caucasian	Other cancer	21/107	Female	PB	PCR-RFLP	0.00
Ollerenshaw M	2004	UK	Caucasian	Renal cell carcinoma	160/288	Mixed	PB	PCR-RFLP	0.00
Tanimoto K	2003	Japan	Asian	Head and neck cancer	55/110	Mixed	PB	PCR-RFLP	0.65
Clifford SC	2001	UK	Caucasian	Renal cell carcinoma	35/143	Mixed	HB	PCR-RFLP	0.00

^aMixed means samples contain both female and male; PB, public based; HB, hospital based; HWE, Hardy-Weinberg equilibrium; PCR, polymerase chain reaction; RFLP, restriction fragment length polymorphism; TaqMan, TaqMan SNP Genotyping Assays.
^bcdThe article of Konac E provided data on three kinds of cancers (cervical cancer, endometrial cancer and ovarian cancer), Konac E-O stands for ovarian cancer; Konac E-C stands for cervical cancer; Konac E-E stands for endometrial cancer.

Back to article page

ISSN: 1475-2867

Contact us

General enquiries: journalsubmissions@springernature.com

Cancer Cell International

Contact us