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Figure 4 | Cancer Cell International

Figure 4

From: An estrogen analogue and promising anticancer agent refrains from inducing morphological damage and reactive oxygen species generation in erythrocytes, fibrin and platelets: a pilot study

Figure 4

Transmission electron microscopy images of control and ESE-16-treated platelets and erythrocytes. Plasma control samples showed normal morphology of platelets including granularity (α- and dense granules) and presence of mitochondria (A scale indicates 2 μm &B scale indicates 1 μm). Platelets exposed to ESE-16 indicated no effect on platelet morphology or interior cellular structures and granularity of the platelets remained intact (C scale indicates 2 μm &D scale indicates 1 μm). Whole blood control samples indicated normal morphology of erythrocytes (E & F - scale indicates 2 μm). Whole blood exposed to ESE-16 showed no significant damage or structural changes to the morphology or membrane of erythrocytes (G & H - scale indicates 2 μm).

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