Table 1 Association of nestin expression with clinicopathological features in ESCC
| Â | Characteristics | No. of patients | Nestin expression n(%) | P-value* | |
|---|---|---|---|---|---|
Positive | Negative | ||||
Gender | Male | 72 | 24 (33.3) | 48 (66.7) | 0.686 |
| Â | Female | 21 | 8 (38.1) | 13 (61.9) | Â |
Age (y) | ≤ 60 | 51 | 16 (31.4) | 35 (68.6) | 0.497 |
| Â | > 60 | 42 | 16 (38.1) | 26 (61.9) | Â |
Differentiation | Poor | 32 | 6 (18.7) | 26 (81.3) | 0.070 |
| Â | Moderate | 44 | 19 (43.2) | 25 (56.8) | Â |
| Â | Well | 17 | 7 (41.2) | 10 (58.8) | Â |
TNM stage | I | 5 | 1 (20) | 4 (80) | 0.133 |
| Â | II | 56 | 23 (41.1) | 33 (58.9) | Â |
|  | III + IV | 32 | 9 (30.8) | 23 (69.2) |  |
Lymph nodes | Positive | 34 | 9 (26.5) | 25 (73.5) | 0.221 |
| Â | Negative | 59 | 23 (39.0) | 36 (61.0) | Â |
Ki67 expression | Positive | 53 | 23 (43.4) | 30 (56.6) | 0.036 |
| Â | Negative | 40 | 9 (22.5) | 31 (77.5) | Â |
PCNA expression | Positive | 56 | 26 (46.4) | 30 (53.6) | 0.003 |
| Â | Negative | 37 | 6 (16.2) | 31 (83.8) | Â |
CDK5 expression | Positive | 50 | 23 (46.0) | 27 (54.0) | 0.022 |
| Â | Negative | 43 | 10 (23.3) | 33 (76.7) | Â |
P35 expression | Positive | 45 | 24 (53.3) | 21 (46.7) | 0.031 |
| Â | Negative | 48 | 15 (31.2) | 33 (68.8) | Â |