Skip to main content
Figure 2 | Cancer Cell International

Figure 2

From: Metformin inhibition of neuroblastoma cell proliferation is differently modulated by cell differentiation induced by retinoic acid or overexpression of NDM29 non-coding RNA

Figure 2

Metformin antiproliferative effects towards neuroblastoma cell lines with different malignant potential. A) Cell counting assay in SH-SY5Y cells, untreated (CTR) or treated with metformin (Met). Y-axis is referred to cell number × 106. B) Cell viability analysis of SH-SY5Y cells untreated (CTR) or treated with metformin (Met), as determined by ATPlite assay. Y-axis is referred to luminescence × 105. C) Cell death quantification by FACS analysis for SYTOX blue staining in untreated (CTR) or metformin (Met)-treated cells. The percentage of cell death is reported as Met/CTR ratio. (*p < 0.05; **p < 0.01).

Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us