Figure 4

Repression of CCN2/CTGF transcription by methylation. Antibodies distributed over the membrane of the liposome vesicle, could be used to recognize target cells as: Ovarian tumor cells, breast tumor cells or hiperproliferative fibroblast during wound healing. It might allow more specificity in the blockage. The DNA methyl-transferase enzyme linked to specific primer for CCN2/CTGF promoter region is located inside the lipofection body. The rational allow us to imagine that CCN2/CTGF gene hipermethylation will promote its downexpression. CCN2/CTGF Primers forward 5′ GAGACAGCCAGTGCGACTC 3′ Reverse 3′ CGGGCTGTCGTCTCGG 5′.