Figure 2
From: PTOP and TRF1 help enhance the radio resistance in breast cancer cell
SF2 in different generation. A and B demonstrated the changes among non-irradiated group and irradiated groups. All the irradiated groups in 2A and 2B were increased greatly than the non-irradiated cell (MDA-MB-435 s). Although a slight decrease were observed along the generation, all the values of SF2 were significant higher than the MDA-MB-435 s cell. The SF2 of parent cell were 0.3655 ± 0.0334, the 1st, 5thand 8th generation of 60/6 cell lines were 0.5224 ± 0.0534, 0.5628 ± 0.0611, 0.5387 ± 0.0225, respectively. The 1st, 5th and 8th generation of 60/2 were 0.5224 ± 0.0534, 0.5627 ± 0.0611, 0.4687 ± 0.0225, respectively. Compare with the parent cell line, the 60/6 and 60/2 cell lines all increased their radio resistivity and stay persistent, p < 0.05.