Figure 2

Quantification of volume density differences of endothelial cell pseudopods in the tumor cortex, within 100 to 150 μm of the well-vascularized tumor capsule, and in the subcortical region at a distance of greater than 150 μm beneath the tumor capsule. The mean ± SEM of the pseudopod volume density of 10 tumors in the two different regions of the tumors indicate a significant (p < 0.001) three fold higher value of pseudopod volume density in the subcortical region compared to the cortical region of the tumor.