Table 2 NMR peak ratios measured on K562wt and K562adr spectra. Cells were incubated for 2 hours in RPMI, or in RPMI containing methyl-β-cyclodextrin 5 mM (MCD). Results are expressed as means of arbitrary units ± SD multiplied by tenStatistical analysis : *: P < 0.05 when compared with RMPI incubated cells.
K562wt | K562adr | |||
|---|---|---|---|---|
Group | RPMI (n = 6) | MCD (n = 5) | RPMI (n = 4) | MCD (n = 4) |
CH3/Ct | 50 ± 5 | 101 ± 22* | 34 ± 3 | 34 ± 2 |
CH2/Ct | 247 ± 35 | 537 ± 13* | 142 ± 22 | 130 ± 18 |
N+(CH3)3/Ct | 23 ± 3 | 22 ± 7 | 17 ± 3 | 21 ± 16 |