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Figure 5 | Cancer Cell International

Figure 5

From: Changes in P-glycoprotein activity are mediated by the growth of a tumour cell line as multicellular spheroids

Figure 5

Comparative doxorubicin retention of PSC-1 cells and INER-51 cells. PSC-1 tumour cells growth as monolayers (filled circles) or multicellular spheroids (filled triangles) and INER-51 monolayers (open circles) or multicellular spheroids (open triangles) were incubated with increased concentrations of DXR (as in Figure 1) and then intracellular fluorescence was determined by spectrofluormetry. Insert box. Rhodamine-123-retention in PSC-1 cell growth as monolayers or multicellular spheroids.

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