Effects of chemical treatment on expression of genes involved in DNA replication initiation and CYP1B1. mRNA levels in A549 cells that were treated as described in Fig. 1 were measured using cDNA microarray hybridization and protein levels by Western blotting. A. mRNA levels of DNA replication initiation genes. B. mRNA levels of CYP1B1 C. Expression of CYP1B1 protein. GenBank accession number for each gene is displayed in table 1.