Table 2 P-gp and adhesion molecule expression of MDR1-transfected human breast carcinoma cell lines as percent positive cells, and mAb binding sites (× 104)
| Â | MDA-MB | MPAM-26 | MPAH1-10 | MPAH1-300 | MPAHDOX |
|---|---|---|---|---|---|
MRK16 = A | 12.07 | 8.52 | 30.57 | 56.47 | 78.50 |
s.d. | 4.10 | 1.62 | 10.85 | 3.20 | 9.68 |
MRK16 = B | 5.45 | 3.00 | 4.41 | 12.85 | 38.36 |
s.d | 0.21 | 0.56 | 0.35 | 2.79 | 10.23 |
ICAM-1 = A | 58.65 | 59.39 | 62.63 | 55.13 | 76.36 |
s.d. | 1.79 | 2.03 | 4.56 | 7.44 | 1.41 |
ICAM1 = B | 16.43 | 13.36 | 12.66 | 19.00 | 35.54 |
s.d. | 1.20 | 3.48 | 4.80 | 8.81 | 12.25 |
LFA-3 = A | 82.37 | 83.12 | 83.30 | 84.12 | 89.38 |
s.d. | 2.31 | 1.27 | 6.71 | 4.84 | 1.42 |
LFA-3 = B | 23.65 | 24.65 | 18.08 | 33.22 | 53.66 |
s.d. | 11.36 | 3.31 | 3.41 | 6.20 | 9.64 |
CD18 = A | 2.44 | 0.13 | 9.69 | 18.43 | 0.17 |
s.d. | 1.35 | 3.52 | 2.52 | 3.26 | 0.93 |
CD18 = B | 7.44 | 5.66 | 5.24 | 7.77 | 7.58 |
s.d. | 1.31 | 1.72 | 1.35 | 1.57 | 1.76 |
CD56 = A | 3.72 | 0.58 | 4.18 | 0.44 | 0.33 |
s.d. | 2.13 | 0.44 | 5.88 | 0.75 | 0.57 |
CD56 = B | 6.92 | 4.90 | 3.97 | 5.97 | 5.93 |
s.d. | 0.91 | 1.20 | 0.81 | 1.29 | 0.07 |