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Table 3 Mutations of C to other bases in p53 codons 210–290

From: Mechanisms of genotoxin-induced transcription and hypermutation in p53

  A G T
Total C mutations including lung (1875) 157 187 1531
Percent of total 8.4% 10.0% 81.6%
Lung C mutations (198) 21 31 146
Percent of lung 10.6% 15.7% 73.7%
Difference in total C mutations due to the presence of lung C mutations +2.2% +5.7% -7.9%
  1. All point mutations in codons 210–290 were analyzed.
  2. In Table 3, the ultimate fate of C mutations in all cancers due to the presence of lung cancers is shown.
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