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Table 3 Mutations of C to other bases in p53 codons 210–290

From: Mechanisms of genotoxin-induced transcription and hypermutation in p53

 

A

G

T

Total C mutations including lung (1875)

157

187

1531

Percent of total

8.4%

10.0%

81.6%

Lung C mutations (198)

21

31

146

Percent of lung

10.6%

15.7%

73.7%

Difference in total C mutations due to the presence of lung C mutations

+2.2%

+5.7%

-7.9%

  1. All point mutations in codons 210–290 were analyzed.
  2. In Table 3, the ultimate fate of C mutations in all cancers due to the presence of lung cancers is shown.
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Cancer Cell International

ISSN: 1475-2867

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