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Table 5 Mutations of G to other bases in p53 codons 210–290

From: Mechanisms of genotoxin-induced transcription and hypermutation in p53

 

A

C

T

Total G mutations including colon (3375)

2082

351

942

Percent of total

61.7%

10.4%

27.9%

Colon G mutations (317)

257

19

41

Percent of colon

81.1%

6.0%

12.9%

Difference in total G mutations due to the presence of colon G mutations

+19.4%

-4.4%

-15.0%

  1. Analyzed as in Tables 1-3 for colon cancer.
  2. Table 5 shows the ultimate fate of G mutations in all cancers due to colon cancers.