Skip to main content

Table 3 A and B: Quantification of VOCs consumed by CALU-1 cancer cells after adsorption on solid sorbents with subsequent TD-GC-MS analyses.

From: Release of volatile organic compounds (VOCs) from the lung cancer cell line CALU-1 in vitro

A

              
    

Concentration [ppbv] after 4 hours of incubation

mean ppb Medium

mean ppb Cells

ppb Cells/ppb Medium

Compound

CAS

R2

LOD [ppbv]

Medium

Cells

   

methacrolein

78-85-3

0,999

0,466

5,66

9,38

3,93

0,63

0,34

0,84

0,34

0,34

4,898

0,469

0,10

2-methylpropanal

78-84-2

0,998

0,143

19,80

12,98

39,53

9,12

1,21

below LOD

3,35

2,03

20,357

1,649

0,08

methyl tert-butyl ether

1634-04-4

0,999

0,293

1,68

3,43

3,56

1,60

0,67

0,94

1,30

1,11

2,567

1,004

0,39

3-methylbutanal

590-86-3

0,994

0,234

142,29

184,19

218,74

73,14

0,08

2,44

3,02

2,13

154,588

1,916

0,01

n-butyl acetate

123-86-4

0,999

0,134

60,47

105,13

66,58

58,08

2,01

14,70

11,27

13,08

72,566

10,267

0,14

B

              

Compound

CAS

R 2

LOD [ppb v ]

Concentration [ppb v ] after 18 hours of incubation

mean ppb Medium

mean ppb Cells

ppb Cells/ppb Medium

     

Medium

Cells

    

acetaldehyde

75-07-0

0,993

1,517

257,527

335,818

315,063

 

below LOD

116,472

81,692

 

302,803

66,054

0,22

acetonitrile

75-05-8

0,998

0,147

11,344

7,540

5,764

 

4,183

3,633

4,100

 

8,216

3,972

0,48

acrolein

107-02-8

0,998

0,718

5,703

3,462

4,079

 

2,185

2,071

3,238

 

4,415

2,498

0,57

methacrolein

78-85-3

0,999

0,466

5,933

4,975

4,723

 

0,811

0,344

0,702

 

5,210

0,619

0,12

2-methylpropanal

78-84-2

0,998

0,143

30,915

11,773

21,277

 

0,532

3,573

0,083

 

21,322

1,396

0,07

2-butanone

78-93-3

0,999

0,149

3,523

5,206

3,084

 

1,114

2,812

1,669

 

3,938

1,865

0,47

methyl tert-butyl ether

1634-04-4

0,999

0,293

2,126

4,202

2,089

 

0,753

1,654

1,023

 

2,806

1,143

0,41

3-methylbutanal

590-86-3

0,994

0,234

157,462

206,895

78,027

 

2,226

2,215

1,529

 

147,461

1,990

0,01

ethyl tert-butyl ether

637-92-3

0,999

0,215

6,168

11,281

5,121

 

2,060

4,805

2,229

 

7,523

3,032

0,40

2-methyl-2-butenal

1115-11-3

0,985

0,430

1,839

1,024

1,163

 

below LOD

below LOD

below LOD

 

1,342

0,000

0,00

hexanal

66-25-1

0,981

0,540

2,043

2,805

1,980

 

0,791

1,016

0,711

 

2,276

0,839

0,37

n-butyl acetate

123-86-4

0,999

0,134

43,949

31,381

26,348

 

11,084

3,032

3,324

 

33,892

5,813

0,17

  1. The concentration of these VOCs is decreased in headspace of CALU-1 cells in comparison with medium only. Two different incubation times were studied: 4 h (A) and 18 h (B). The concentrations of discussed VOCs are given for measured sample (headspace of CALU-1 cells and of medium). The correlation coefficients (for calibration experiments) and the limits of detection (LODs) are presented.
Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us