Figure 2

Expression of Ebp1 in prostate tissues. A) Prostate epithelium stained for Ebp1. Example of the four cytoplasmic staining intensities for Ebp1: 0+, 1+, 2+ and 3+. B) Median staining intensity of Ebp1 in normal (n = 39), normal adjacent (n = 53), PIN (n = 29), tumor (n = 62) and hormone refractory (n = 36) prostate tissues. Normal tissues come from the N-TMA. Normal Adjacent, PIN and tumor tissues come from the RP-TMA. The hormone refractory tissues come from the HR-TMA. Significant statistical differences were found Normal vs Normal Adjacent Tissues (P < 0.001, Mann-U), Normal Adjacent vs Tumor Tissues (P < 0.001, Mann-U), PIN vs Tumor (P = 0.003, Mann-U) and Tumor vs Hormonorefractory (P < 0.001, Mann-U). However, no statistical difference was found between Normal Adjacent vs. PIN (P = 0.464, Mann-U). C) Median staining intensity of Ebp1 according to Gleason score. The tissues analyzed are from the tumor cores of the RP-TMA. No significant differences were observed (Mann-U).