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Figure 4 | Cancer Cell International

Figure 4

From: The stimulatory activity of plasma in patients with advanced non-small cell lung cancer requires TLR-stimulating nucleic acid immunoglobulin complexes and discriminates responsiveness to chemotherapy

Figure 4

Reduced stimulatory activity of plasma in patients who responded to chemotherapy. (A and B) PBMCs derived from normal volunteers were cultured with 20% plasma derived from NSCLC patients who responded to chemotherapy (A) or not responded to chemotherapy (B) before treatment, after the first cycle and after the second cycle of chemotherapy respectively. Data points represented individual patients. *P < 0.01. (C and D) PBMCs derived from NSCLC patients who responded to chemotherapy (C) or not responded to chemotherapy (D) before treatment, after the first cycle and after the second cycle of chemotherapy respectively, and then assayed for their expression of the indicated cytokines. Each bar represented the means (±SD) from 12 responders or 16 nonresponders.

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