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Table 2 Differential gene expression between DLBCL patients with different disease stages at baseline

From: Changes of T-lymphocyte subpopulation and differential expression pattern of the T-bet and GATA-3 genes in diffuse large B-cell lymphoma patients after chemotherapy

  EGR-1 T-bet GATA-3 TGF-β
ΔΔCt1 2-ΔΔCt1 ΔΔCt1 2-ΔΔCt1 ΔΔCt1 2-ΔΔCt1 ΔΔCt2 2-ΔΔCt2
Stage I-II −0.120 ± 0.67 1.09 ± 0.23 −2.496 ± 0.568 5.65 ± 1.05 −3.742 ± 0.714 13.33 ± 2.65 0.723 ± 0.793 0.605 ± 0.51
Stage III-IV −2.952 ± 0.851 7.69 ± 2.10 −4.099 ± 1.272 17.24 ± 4.23 −5.143 ± 1.632 35.71 ± 12.41 1.337 ± 0.931 0.395 ± 0.46
P 0.008* 0.068 0.144 0.092
  1. Note: ΔΔCt1 = ΔCttarget gene in control-ΔCttarget gene in patients,2-ΔΔCt1 indicates the fold decrease in the expression of target genes in patients compared to controls. ΔΔCt2 = ΔCt TGF-β in patient-ΔCt TGF-β in control, 2-ΔΔCt2 indicates the fold increase in TGF-β expression in patients compared to controls. *indicates that there is significant difference between two groups.