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Table 2 Clinicopathologic characteristics, clinical outcomes in breast cancer patients with different HIF-1α 1772 C > T genotypes

From: SNP 1772 C > T of HIF-1α gene associates with breast cancer risk in a Taiwanese population

Genotype CC (%) CT (%) TT (%) pvalue
Case number 53 (55%) 21 (22%) 22 (23%)  
Age     0.117a
 Mean ± SD (years) 46.5 ± 9.7 43.1 ± 10.3 49.4 ± 9.6  
 Range (years) 27 ~ 68 19 ~ 62 31 ~ 73  
Laterality     0.463b
 Left 26 (52%) 10 (20%) 14 (28%)  
 Right 27 (58%) 11 (24%) 8 (17%)  
T-stage     0.303b
 T1 or T2 35 (53%) 13 (20%) 18 (27%)  
 T3 or T4 18 (60%) 8 (27%) 4 (13%)  
N-stage     0.936b
 Node negative 14 (58%) 5 (21%) 5 (21%)  
 Node positive 39 (54%) 16 (22%) 17 (24%)  
HIF-1α expression     0.311b
 Low 34 (51%) 15 (22%) 18 (27%)  
 High 19 (66%) 6 (21%) 4 (14%)  
VEGF expression     0.375b
 Low 18 (62%) 7 (24%) 4 (14%)  
 High 35 (52%) 14 (21%) 18 (27%)  
Microvessel density     0.211b
 Low 32 (63%) 8 (16%) 11 (22%)  
 High 21 (47%) 13 (29%) 11 (24%)  
  1. aby ANOVA test.
  2. bby Chi-Square test.