Table 2 Drug sensitivity of ETCC001 and sub-lines
|  |  | IC50(μM) | ||||||
|---|---|---|---|---|---|---|---|---|
Anti-neoplastic Class | Â | ETCC001 | ETCC006 | ETCC007 | ETCC008 | ETCC010 | ETC011 | MCF7 |
ER antagonist | Tamoxifen | 6.3 | 34.2 | 32.8 | 32.4 | 30.0 | 33.5 | 26.6 |
Monoclonal Ab | Herceptin | >10 | >10 | >10 | >10 | >10 | >10 | Not Done |
Anti-microtubular | Paclitaxel | >100 | >100 | >100 | >100 | >100 | >100 | >100 |
Anti-metabolite | 5-fluorouracil | >100 | >100 | >100 | >100 | >100 | >100 | >100 |
Anti-matabolite | Gemcitabine | >100 | >100 | >100 | >100 | >100 | >100 | >100 |
Alkylating | Cisplatin | >100 | >100 | >100 | >100 | >100 | >100 | >100 |
Anthracycline | Docorubicin | 9.3 | 3.2 | >100 | 77.8 | 5.0 | 20.8 | 12.3 |
Topo I inhibitor | Camptothecin | >100 | >100 | >100 | >100 | >100 | >100 | 4.5 |