Increase of IFN-γ and TNF-γ production in CD107a + NK-92 cells co-cultured with cervical cancer cell lines pre-treated with the HO-1 inhibitor

Table 1 Downmodulation of NCR and NKG2D in NK-92 cells co-cultured with Cervical cancer cell (CCC) lines

CCC HeLa, SiHa, and C-33A were pre-treated with SnPP or ZnPP HO-1 inhibitors. Afterward, transwell assays were performed between NK-92 cells and HeLa, SiHa, and C-33A. Subsequently, the geometric Mean fluorescence intensity (MIF) of NKG2D, NKp30, NKp44, and NKp46 were determined. The Standard deviation (SD) of MIF in all groups did not exceed 135. *P <0.05 SnPP- or ZnPP-treated CCC vs. HeLa, SiHa, and C-33A without treatment.

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