Figure 6

S100A7 knockdown decreases NCI-H520 xenografts growth in vivo. NCI-H520 and knockdown cells were injected into the left flanks for nude mice and tumor size was serially measured until post injection day 35. A. Volume of the tumors over time shows significant growth retardation in the knockdown cells (S4) compared with NCI-H520 or vector control cells (NT) cells (mean ± standard error of the mean; n = 6) per group. B. wild-type tumors exhibit increased Ki-67 expression compared with the knockdown tumors. (^* P < 0.05).