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Table 3 Combined calculated IC50 bupivacaine concentrations (ppm) differentiating only cell type

From: In vitro myotoxic effects of bupivacaine on rhabdomyosarcoma cells, immortalized and primary muscle cells

Incubation/recovery time combined (h)

Differentiated primary muscle cells [IC50 ± SD] (n = 24)

Rhabdomyosarcoma cells [IC50 ± SD] (n = 31)

Immortalized C2C12 cells [IC50 ± SD] (n = 24)

 

1,161 ± 403* ppm

2,034 ± 584* ppm

3,297 ± 1,247* ppm

  1. ANOVA with Bonferroni * p < 0.01.