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Table 1 miR-30b and Cthrc1 mRNA expression levels were associated with clinicopathological features of NSCLC patients

From: microRNA-30b inhibits cell invasion and migration through targeting collagen triple helix repeat containing 1 in non-small cell lung cancer

Clinicopathological factor

n

miR-30b(2−ΔΔCt)

Cthrc1 mRNA(2−ΔΔCt)

Median ± SD

P

Media ± SD

P

Gender

 Male

38

0.2847 ± 0.1138

0.720

2.2714 ± 0.3568

0.707

 Female

24

0.2960 ± 0.1307

 

2.2371 ± 0.3359

 

Age (years)

 ≥60

35

0.3081 ± 0.1324

0.156

2.222 ± 0.3971

0.345

 <60

27

0.2644 ± 0.0979

 

2.305 ± 0.2672

 

Histology

 SCC

21

0.3033 ± 0.0992

0.508

2.2548 ± 0.2960

0.957

 AC

41

0.2818 ± 0.1295

 

2.2599 ± 0.3732

 

Differentiation

 Well

21

0.3455 ± 0.1533

0.007*

2.1035 ± 0.4324

0.011*

 Moderate & Poor

41

0.2602 ± 0.0870

 

2.3374 ± 0.2656

 

TNM

 I

25

0.3540 ± 0.1327

0.000*

2.1010 ± 0.3440

0.005*

 II

23

0.2663 ± 0.0927

 

2.3126 ± 0.2796

 

 III

14

0.2107 ± 0.0677

 

2.4494 ± 0.3470

 

Lymphnode metastasis

 N0

47

0.3129 ± 0.1234

0.005*

2.1952 ± 0.3290

0.010*

 N1–N3

15

0.2147 ± 0.0670

 

2.4555 ± 0.3352

 
  1. SCC squamous cell carcinoma, AC adenocarcinoma
  2. * Indicated statistical significance (P < 0.05)