Table 2 The association between miR-539 expression and characteristics of patients suffering from osteosarcoma
Clinicopathological features | No. of cases, 35 | Expression of miR-539 | P value | |
|---|---|---|---|---|
Low, 21 | High, 14 | |||
Gender | ||||
Male | 15 | 9 | 6 | NS |
Female | 20 | 12 | 8 | |
Age | ||||
≤40 | 19 | 10 | 9 | NS |
>40 | 16 | 11 | 5 | |
Tumor diameter (cm) | ||||
≤5 | 21 | 11 | 10 | NS |
>5 | 14 | 10 | 4 | |
Differentiation | ||||
Well and moderate | 18 | 9 | 9 | NS |
Poor | 17 | 12 | 5 | |
TNM stage | ||||
I + II | 12 | 5 | 7 | 0.001 |
III + IV | 23 | 16 | 7 | |
Metastasis or recurrence | ||||
Yes | 22 | 16 | 6 | 0.01 |
No | 13 | 5 | 8 | |