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Fig. 2 | Cancer Cell International

Fig. 2

From: Targeting colorectal cancer stem cells using curcumin and curcumin analogues: insights into the mechanism of the therapeutic efficacy

Fig. 2

Mechanism of action of curcumin on cancer cells and cancer stem cells by targeting the self-renewal signalling pathways. Curcumin modulates the fate of cancer stem cell by targeting misregulated signalling pathways at multiple cellular levels namely; receptors, downstream effectors and transcriptional activity in a Hedgehog, b Notch, c PI3K/Akt/mTOR and d Wnt/β-catenin signalling pathways

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