Morphological and molecular characterization of the human breast epithelial cell line M13SV1 and its tumorigenic derivatives M13SV1-R2-2 and M13SV1-R2-N1

Table 2 Summary of the network analysis

	Activation status	p-value	z-score
Upstream regulator
ERBB2	Activated	1.27E−05	1.117
RAF1	Activated	7.60E−07	0.447
TGFB1	Activated	1.22E−03	0.681
WISP2	Inhibited	3.29E−03	−0.762
Biological function
Migration of breast cancer cell lines	Activated	2.44E−04	1.313
Cell viability of breast cancer cell lines	Inhibited	1.64E−02	−1.346
Cell death of breast cancer cell lines	Activated	3.52E−02	1.339
Apoptosis of breast cancer cell lines	Activated	2.87E−02	1.116

Upstream regulators and biological functions that are activated or inhibited in the R2-N1 cell line in comparison to the parent cell line M13SV1 according to the results of the IPA analysis

ISSN: 1475-2867