Fig. 4

Baseline and growth factor-induced proliferation of HGSOC cell lines. a Baseline proliferation varied across the six HGSOC cell lines and treatment with 10 ng/mL HB-EGF, NRG1β, IGF1, or HGF for 24 h induced proliferation in a subset of these cell lines. Proliferation was determined by Click-iT EdU and flow cytometry. Data presented as the average ± SD, n = 3. *p < 0.05 compared to vehicle. b Representative flow cytometry histograms for each cell line-growth factor condition, with the percentage of EdU-positive cells (cells in S-phase) indicated