Fig. 8
From: The effects of MOTILIPERM on cisplatin induced testicular toxicity in Sprague–Dawley rats
Schematic view of endoplasmic reticulum (ER) stress signaling pathway explained. GRP78 Glucose-regulated protein-78 (GRP-78), pIRE1 phosphorylated inositol-requiring transmembrane kinase/endoribonuclease1; IRE1 inositol-requiring transmembrane kinase/endoribonuclease1; ATF6 activating transcription factor-6; TRAF2 tumor necrosis factor receptor associated factor2; PERK protein kinase RNA-like endoplasmic reticulum kinase; ASK1 apoptosis signal-regulating kinase; pJNK phosphorylated c-jun-N-terminal kinase; JNK c-jun-N-terminal kinase