Fig. 3From: Solamargine triggers cellular necrosis selectively in different types of human melanoma cancer cells through extrinsic lysosomal mitochondrial death pathwayFlow cytometry analysis showed, Solamargine increased apoptosis tenfold more in malignant to benign cells. 10 µM Solamargine treatment for 2 h selectively caused massive cellular death of WM115 primary and WM239 metastatic melanoma cells which was at least tenfold more than the detected in benign WM35 and/or in BAEC cells.The results shown are for one representative experiment of triplicate determinationsBack to article page