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Fig. 2 | Cancer Cell International

Fig. 2

From: Paclitaxel and the dietary flavonoid fisetin: a synergistic combination that induces mitotic catastrophe and autophagic cell death in A549 non-small cell lung cancer cells

Fig. 2

The combined effect of fisetin (FIS) and paclitaxel (PTX) on other solid tumor cell lines. Logarithmic combination index plot (Fa-log(CI) plot) for FIS and PTX co-treatment in a the human colon adenocarcinoma LoVo cells b the human non-small cell lung cancer H1229 cells c the human breast adenocarcinoma MCF-7 cells. CI values (logarithmic) are plotted as a function of the fractional inhibition (fa) of cell viability/growth by computer simulation (CompuSyn software) from 0.1 to 0.95. Triangles represent CI values derived from the actual experimental points. In the Fa-log(CI) plot, the synergism is indicated by a negative value (log(CI) < 0), antagonism is indicated by a positive value (log(CI) > 0), and additive effect (denoted by a dashed line) is indicated by 0 (log(CI) = 0)

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Cancer Cell International

ISSN: 1475-2867

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