Table 3 The top five enriched gene ontology (GO) terms functional enrichment of the differentially expressed genes
GO ID | Term | Gene counts | P value | |
|---|---|---|---|---|
Up-regulated genes | GO:0006955 | Immune response | 104 | 9.10E−18 |
GO:0001775 | Cell activation | 54 | 3.82E−13 | |
GO:0002684 | Positive regulation of immune system process | 47 | 2.70E−12 | |
GO:0050865 | Regulation of cell activation | 39 | 5.70E−12 | |
GO:0045321 | Leukocyte activation | 46 | 1.86E−11 | |
Down-regulated genes | GO:0055114 | Oxidation reduction | 132 | 2.56E−16 |
GO:0006091 | Generation of precursor metabolites and energy | 80 | 2.93E−15 | |
GO:0006811 | Ion transport | 141 | 4.19E−13 | |
GO:0006818 | Hydrogen transport | 29 | 1.38E−12 | |
GO:0015992 | Proton transport | 28 | 3.91E−12 |