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Fig. 1 | Cancer Cell International

Fig. 1

From: MiR-519d facilitates the progression and metastasis of cervical cancer through direct targeting Smad7

Fig. 1

The impact of miR-519d inhibition on the proliferation and viability of cervical cancer cells. a, b The efficiency of miR-519d inhibitor has been detected by real-time PCR in Hela and SiHa cells (*P < 0.05). c, d HeLa and SiHa were subjected to MTT assay at different time periods (24, 48, 72 and 96 h) following transfection with NC miRNA or miR-519d inhibitor (*P < 0.05). e Annexin/PI apoptotic assay was performed to determine the proportion of apoptotic cells in HeLa and SiHa following transfection with NC miRNA or miR-519d inhibitor, along with 10 μM 5-FU treatment. f Statistical analysis of the proportion of apoptotic cells in the indicated groups (*P < 0.05). g Flow cytometrical analysis of cell cycle distribution of HeLa and SiHa cells following transfection with NC miRNA or miR-519d inhibitor (*P < 0.05)

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Cancer Cell International

ISSN: 1475-2867

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