Calreticulin mediates an invasive breast cancer phenotype through the transcriptional dysregulation of p53 and MAPK pathways

Table 1 Statistical analysis of immunohistochemistry results for calreticulin expression (ANOVA)

Stage	Sum of squares	df	Mean square	F	Sig.
Glandular tissue
Between groups	10.854	3	3.618	0.777	0.516
Within groups	139.617	30	4.654
Total	150.471	33
Stroma
Between groups	60.128	3	20.043	4.985	0.005
Within groups	164.85	41	4.021
Total	224.978	44
Invasive carcinoma
Between groups	28.301	2	14.15	3.213	0.053
Within groups	145.338	33	4.404
Total	173.639	35

One-way ANOVA showed significantly higher calreticulin expression in stromal parts of malignant tissues as compared to non-malignant samples (p < 0.05)

ISSN: 1475-2867