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Table 2 The 10 most up/downregulated genes upon knockdown of CRT expression

From: Calreticulin mediates an invasive breast cancer phenotype through the transcriptional dysregulation of p53 and MAPK pathways

Gene name

Systematic name

Log FC

p value

IFIT1

NM_001548

2.9

0.00065

IFIT2

NM_001547

2.5

2.10E−05

IFI6

NM_022873

2.3

0.00016

IFIT3

NM_001549

2.3

0.00033

IFI27

NM_005532

2.2

0.0034

DDX58

NM_014314

2

7.20E−06

DDX60

NM_017631

2

5.00E−05

IFI27

NM_005532

2

0.0045

OASL

NM_003733

1.9

2.10E−05

SAMD9

NM_017654

1.9

7.30E−05

CALR

NM_004343

−2.7

5.20E−15

MNT

AF318360

−2.1

2.30E−13

CA306742

CA306742

−1.5

9.30E−12

FAM35A

NM_019054

−0.67

4.90E−06

PCNXL3

NM_032223

−0.58

2.00E−07

C13orf37

NM_001071775

−0.57

2.70E−06

TACC2

NM_206862

−0.56

0.00025

ENST00000301038

ENST00000301038

−0.5

5.40E−07

CPOX

NM_000097

−0.46

0.00037

TAOK3

NM_016281

−0.46

0.0023

  1. Genes are listed based on their names, systematic names, fold changes in their expression (log FC) and the p values. CRT as the most down-regulated gene is shown in bold