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Fig. 5 | Cancer Cell International

Fig. 5

From: KIAA0101, a target gene of miR-429, enhances migration and chemoresistance of epithelial ovarian cancer cells

Fig. 5

KIAA0101 is targeted by miR-429. a The putative binding sites of miR-429 on the KIAA0101 3′-UTR region. b Wild type (WT) of KIAA01013′-UTR region was mutated. c Luciferase activities in SKOV3 and COV644 cells 48 h after co-transfected with KIAA0101 3′-UTR wild type or mutant (Mut) luciferase plasmid and miR-429 or miR-Control. **p < 0.01 compared to miR-Control transfected cells. d Levels of KIAA0101 protein was determined by Western blot in SKOV3 and COV644 cells transfected with miR-429 or miR-Control. e The correlation of the expression levels of KIAA0101 and miR-429 in 40 EOC tissue samples (r = −0.648, p < 0.001)

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