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Table 1 Clinicopathologic features of BC patients and the levels of DBCCR1-003 and DNMT1 expression in the cancer tissues

From: Long non-coding RNA DBCCR1-003 regulate the expression of DBCCR1 via DNMT1 in bladder cancer

Characteristic Number of patients Molecular expression level
   DBCCR1-003c p value DNMT1d p value
All patients 24 (100 %)     
Gendera    0.403   0.639
 Females 10 (41.6 %) 4.61 (1.10–4.19)   1.68 (1.2–2.39)  
 Males 14 (58.4 %) 1.60 (0.56–3.70)   1.87 (0.65–3.43)  
Age at diagnosisa    0.887   0.931
 ≤70 years 12 (50.0 %) 2.0 (0.58–3.70)   1.85 (0.65–3.43)  
 >70 years 12 (50.0 %) 1.91 (0.56–4.19)   1.74 (0.97–2.39)  
Pathologic gradea    0.02*   0.035*
 Low grade 8 (33.3 %) 2.90 (1.39–4.19)   1.4 (0.97–2.19)  
 High grade 16 (66.7 %) 1.39 (0.57–2.81)   1.98 (1.15–3.43)  
Pathologic stageb    0.14   0.037*
 pTa 5 (20.8 %) 3.39 (2.51–4.19)   1.26 (0.65–1.84)  
 pT1 13 (54.2 %) 1.84 (0.66–3.70)   1.74 (1.0–2.39)  
 ≥pT2 6 (25.0 %) 1.02 (0.57–1.57)   2.34 (1.35–2.71)  
  1. * Significant difference
  2. aEvaluated with the Mann–Whitney U-test
  3. bEvaluated with the Kruskal–Wallis test
  4. cLevels of DBCCR1-003 expression were determined by qRT–PCR assay, and normalized to the U6 levels using the 2CTCT method
  5. dLevels of DNMT1 expression were determined by qRT–PCR assay, and normalized to the GAPDH levels using the 2CTCT method