Skip to main content

Table 1 Clinicopathologic features of BC patients and the levels of DBCCR1-003 and DNMT1 expression in the cancer tissues

From: Long non-coding RNA DBCCR1-003 regulate the expression of DBCCR1 via DNMT1 in bladder cancer

Characteristic

Number of patients

Molecular expression level

  

DBCCR1-003c

p value

DNMT1d

p value

All patients

24 (100 %)

    

Gendera

  

0.403

 

0.639

 Females

10 (41.6 %)

4.61 (1.10–4.19)

 

1.68 (1.2–2.39)

 

 Males

14 (58.4 %)

1.60 (0.56–3.70)

 

1.87 (0.65–3.43)

 

Age at diagnosisa

  

0.887

 

0.931

 â‰¤70 years

12 (50.0 %)

2.0 (0.58–3.70)

 

1.85 (0.65–3.43)

 

 >70 years

12 (50.0 %)

1.91 (0.56–4.19)

 

1.74 (0.97–2.39)

 

Pathologic gradea

  

0.02*

 

0.035*

 Low grade

8 (33.3 %)

2.90 (1.39–4.19)

 

1.4 (0.97–2.19)

 

 High grade

16 (66.7 %)

1.39 (0.57–2.81)

 

1.98 (1.15–3.43)

 

Pathologic stageb

  

0.14

 

0.037*

 pTa

5 (20.8 %)

3.39 (2.51–4.19)

 

1.26 (0.65–1.84)

 

 pT1

13 (54.2 %)

1.84 (0.66–3.70)

 

1.74 (1.0–2.39)

 

 â‰¥pT2

6 (25.0 %)

1.02 (0.57–1.57)

 

2.34 (1.35–2.71)

 
  1. * Significant difference
  2. aEvaluated with the Mann–Whitney U-test
  3. bEvaluated with the Kruskal–Wallis test
  4. cLevels of DBCCR1-003 expression were determined by qRT–PCR assay, and normalized to the U6 levels using the 2−△CT△CT method
  5. dLevels of DNMT1 expression were determined by qRT–PCR assay, and normalized to the GAPDH levels using the 2−△CT△CT method
Back to article page

Cancer Cell International

ISSN: 1475-2867

Contact us