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Fig. 4 | Cancer Cell International

Fig. 4

From: The inhibition role of miR-22 in hepatocellular carcinoma cell migration and invasion via targeting CD147

Fig. 4

miR-22 negatively regulates CD147 gene expression. miR-22 inhibited the expression of CD147 at the mRNA level a and the protein level b in MHCC-97H and SMMC-7721 cells. c IHC analysis of CD147 protein expression in HCC and paired adjacent normal tissues. Pictures of representative areas are presented at different staining intensities (weak and strong) in ANT and tumor tissues. Scale bars, 50 μm. d Analysis for correlation of miR-22 mRNA and CD147 protein expression in HCC tissues

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