Fig. 5

Knockdown of HGMB2 inhibited the GC cell proliferation. a CCK8 cell proliferation was performed to detect the cell abilities after HMGB2 down-regulation in MKN45 cells. b The protein expression of PCNA and Ki-57 was determined by western-blotting analysis in MKN45 cells. **P < 0.05, the results were represented as the average ± SD based on 3 independent experiments