Fig. 1

BBR inhibits cell viability and proliferation. a HepG2, b Hep3B and c SNU-182 cells were treated with various doses of BBR (0, 10, 20, 50, and 100 μM) for 24 and 72 h. Cells viability were detected by MTS assay. d Cell numbers were counted after treated with various doses of BBR (0, 10, 20, 50) for 72 h. All experiments were repeated 3 times (n = 3). All data are depicted as mean ± SEM (error bars), (*p < 0.05; **p < 0.01 vs. BBR 0 μM)